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Table 1 Pandemic COVID-negative and pre-pandemic matched cohort composition and mortality (n = 123,133 for both cohorts)

From: Excess mortality in COVID-19-negative people with non-communicable disorders during the first pandemic wave

 

Pre-pandemic Cohort

(2018)

Pandemic Cohort

(2020)

Pre-pandemic Cohort

(2018)

Pandemic Cohort

(2020)

 

Subgroup Characteristics

n (% of cohort)

Subgroup Deaths

n (% of cohort)

Sex

    

 Female

74,021 (60.1)

74,011 (60.1)

1,242 (1.0)

3,030 (2.5)

 Male

49,112 (39.9)

49,122 (39.9)

1,345 (1.1)

3,642 (3.0)

Age in Years

    

 18–40

43,023 (34.9)

43,043 (35.0)

80 (0.1)

193 (0.2)

 41–60

41,774 (33.9)

41,773 (33.9)

239 (0.2)

704 (0.6)

 61–70

16,248 (13.2)

16,288 (13.2)

327 (0.3)

943 (0.8)

 71–80

10,968 (8.9)

10,972 (8.9)

513 (0.4)

1,555 (1.3)

 81+

11,120 (9.0)

11,057 (9.0)

1,428 (1.2)

3,277 (2.7)

Disorder Categorya

    

 No Previous NCD Morbidity

33,889 (27.5)

33,889 (27.5)

51 (< 0.1)

322 (0.3)

 Immune System-Related

5,045 (4.1)

5,092 (4.1)

239 (0.2)

577 (0.5)

 Cardiovascular

46,478 (37.7)

46,426 (37.7)

2,096 (1.7)

5,052 (4.1)

 Endocrine & Metabolic

37,098 (30.1)

37,093 (30.1)

1,604 (1.3)

3,650 (3.0)

 Cancer

17,159 (13.9)

17,179 (14.0)

998 (0.8)

2,230 (1.8)

 3 or More Morbidities

29,029 (23.6)

29,019 (23.6)

1,968 (1.6)

4,155 (3.4)

 Mental Disorders

47,490 (38.6)

47,413 (38.5)

1,743 (1.4)

3,553 (2.9)

 Chronic Respiratory Diseases

21,305 (17.3)

21,301 (17.3)

1,210 (1.0)

2,446 (2.0)

 Chronic Kidney Diseases

7,647 (6.2)

7,672 (6.2)

926 (0.8)

1,701 (1.4)

 Chronic Liver Diseases

3,827 (3.1)

3,851 (3.1)

238 (0.2)

428 (0.3)

 Substance Use Disorders

8,199 (6.7)

8,210 (6.7)

414 (0.3)

733 (0.6)

Severity Categoryb

    

 No Hospitalization in Prior Year

107,528 (87.3)

107,497 (87.3)

1,003 (0.8)

3,885 (3.2)

 Hospitalized in Prior Year

15,605 (12.7)

15,636 (12.7)

1,584 (1.3)

2,787 (2.3)

 1–27 Days Hospitalized in Prior Year

12,592 (10.2)

12,579 (10.2)

908 (0.7)

1,952 (1.6)

 ≥28 Days Hospitalized in Prior Year

3,013 (2.4)

3,057 (2.5)

676 (0.5)

835 (0.7)

 No ICU in Prior Year

121,166 (98.4)

121,142 (98.4)

2,350 (1.9)

6,248 (5.1)

 With ICU in Prior Year

1,967 (1.6)

1,991 (1.6)

237 (0.2)

424 (0.3)

  1. aIndividuals with multiple pre-existing chronic disorders are included in all applicable disorder categories, so percentages sum to greater than 100
  2. bBased on hospital admissions in the year prior to the exposure or reference year (i.e., 2017 for the pre-pandemic cohort, 2019 for the pandemic cohort). Individuals are included only once per category (i.e., hospitalization or no hospitalization, ICU or no ICU), so percentages sum to 100
  3. ICU = intensive care units. NCD = non-communicable disorder