Table 1 Baseline characteristics
|  | Level | Overall | CumTyG < 8.61 and CumhsCRP < 1 mg/L | CumTyG < 8.61 and 1 ≤ CumhsCRP < 3 mg/L | CumTyG < 8.61 and CumhsCRP ≥ 3 mg/L | CumTyG > 8.61 and CumhsCRP < 1 mg/L | CumTyG > 8.61 and 1 ≤ CumhsCRP < 3 mg/L | CumTyG > 8.61 and CumhsCRP ≥ 3 mg/L | P_value |
|---|---|---|---|---|---|---|---|---|---|
n | Â | 47,310 | 9082 | 9557 | 5016 | 6088 | 10,920 | 6647 | Â |
Age (mean (SD)) |  | 53.05(11.89) | 47.24(9.78) | 49.42(10.92) | 53.56(11.73) | 53.99(11.53) | 56.22(11.66) | 59.76(11.28) | < 0.001 |
Sex (%) | Women | 10,740(22.70) | 2326(25.61) | 2088(21.85) | 1207(24.06) | 1230(20.20) | 2240(20.51) | 1649(24.81) | < 0.001 |
| Â | Men | 36,570(77.30) | 6756(74.39) | 7469(78.15) | 3809(75.94) | 4858(79.80) | 8680(79.49) | 4998(75.19) | Â |
Education (%) | Middle school and below | 34,789(73.53) | 6018(66.26) | 6807(71.23) | 4014(80.02) | 4322(70.99) | 8198(75.07) | 5430(81.69) | < 0.001 |
| Â | High school and above | 12,521(26.47) | 3064(33.74) | 2750(28.77) | 1002(19.98) | 1766(29.01) | 2722(24.93) | 1217(18.31) | Â |
Occupation (%) | Mental | 6918(14.62) | 1431(15.76) | 1375(14.39) | 654(13.04) | 938(15.41) | 1698(15.55) | 822(12.37) | < 0.001 |
| Â | Physical | 40,392(85.38) | 7651(84.24) | 8182(85.61) | 4362(86.96) | 5150(84.59) | 9222(84.45) | 5825(87.63) | Â |
Smoking status (%) | Never | 28,945(61.18) | 5421(59.69) | 5590(58.49) | 3098(61.76) | 3715(61.02) | 6676(61.14) | 4445(66.87) | < 0.001 |
| Â | Former | 2210(4.67) | 346(3.81) | 409(4.28) | 225(4.49) | 303(4.98) | 563(5.16) | 364(5.48) | Â |
| Â | Current | 16,155(34.15) | 3315(36.50) | 3558(37.23) | 1693(33.75) | 2070(34.00) | 3681(33.71) | 1838(27.65) | Â |
Alcohol consumption (%) | Never | 30,406(64.27) | 5571(61.34) | 5984(62.61) | 3488(69.54) | 3685(60.53) | 6908(63.26) | 4770(71.76) | < 0.001 |
| Â | Former | 282(0.60) | 38(0.42) | 41(0.43) | 25(0.50) | 31(0.51) | 77(0.71) | 70(1.05) | Â |
| Â | Current | 16,622(35.13) | 3473(38.24) | 3532(36.96) | 1503(29.96) | 2372(38.96) | 3935(36.03) | 1807(27.19) | Â |
Tea consumption (%) | No | 37,592(79.46) | 7053(77.66) | 7429(77.73) | 4140(82.54) | 4805(78.93) | 8617(78.91) | 5548(83.47) | < 0.001 |
| Â | Yes | 9718(20.54) | 2029(22.34) | 2128(22.27) | 876(17.46) | 1283(21.07) | 2303(21.09) | 1099(16.53) | Â |
BMI (mean (SD)) |  | 25.14(3.37) | 23.70(2.97) | 24.89(3.30) | 25.43(3.68) | 24.71(3.00) | 25.85(3.16) | 26.45(3.55) | < 0.001 |
Fatty liver (%) | No | 27,643(58.43) | 6897(75.94) | 6031(63.11) | 2886(57.54) | 3900(64.06) | 5249(48.07) | 2680(40.32) | < 0.001 |
| Â | Yes | 19,667(41.57) | 2185(24.06) | 3526(36.89) | 2130(42.46) | 2188(35.94) | 5671(51.93) | 3967(59.68) | Â |
HDL-C (median [IQR]) |  | 1.47[1.23,1.80] | 1.54[1.27,1.89] | 1.52[1.26,1.84] | 1.48[1.23,1.79] | 1.46[1.24,1.80] | 1.44[1.22,1.75] | 1.39[1.17,1.66] | < 0.001 |
LDL-C (median [IQR]) |  | 2.60[2.14,3.09] | 2.46[2.08,2.87] | 2.60[2.19,3.02] | 2.33[1.45,2.91] | 2.65[2.25,3.09] | 2.79[2.32,3.29] | 2.70[2.00,3.30] | < 0.001 |
TC (median [IQR]) |  | 4.90[4.30,5.53] | 4.71[4.18,5.20] | 4.74[4.16,5.29] | 4.76[4.17,5.38] | 5.00[4.41,5.64] | 5.08[4.48,5.77] | 5.17[4.53,5.89] | < 0.001 |
Lipid-lowering drugs (%) | No | 46,843(99.01) | 9043(99.57) | 9472(99.11) | 4945(98.58) | 6038(99.18) | 10,805(98.95) | 6540(98.39) | < 0.001 |
Yes | 467(0.99) | 39(0.43) | 85(0.89) | 71(1.42) | 50(0.82) | 115(1.05) | 107(1.61) | Â | |
Hypoglycemic drugs (%) | No | 45,374(95.91) | 8984(98.92) | 9385(98.20) | 4871(97.11) | 5805(95.35) | 10,265(94.00) | 6064(91.23) | < 0.001 |
Yes | 1936(4.09) | 98(1.08) | 172(1.80) | 145(2.89) | 283(4.65) | 655(6.00) | 583(8.77) | Â | |
Yes | 1136(2.40) | 237(2.61) | 229(2.40) | 87(1.73) | 164(2.69) | 283(2.59) | 136(2.05) | Â | |
Hypertension (%) | No | 39,834(84.25) | 8338(91.89) | 8467(88.67) | 4218(84.11) | 5161(84.79) | 8662(79.37) | 4988(75.08) | < 0.001 |
Yes | 7448(15.75) | 736(8.11) | 1082(11.33) | 797(15.89) | 926(15.21) | 2251(20.63) | 1656(24.92) | Â | |
Diabetes (%) | No | 45,135(95.41) | 8965(98.72) | 9359(97.94) | 4850(96.71) | 5769(94.76) | 10,176(93.19) | 6016(90.52) | < 0.001 |
Yes | 2171(4.59) | 116(1.28) | 197(2.06) | 165(3.29) | 319(5.24) | 744(6.81) | 630(9.48) | Â | |
Hyperlipidemia (%) | No | 44,540(94.15) | 8815(97.06) | 9149(95.73) | 4746(94.64) | 5701(93.64) | 10,065(92.17) | 6064(91.23) | < 0.001 |
Yes | 2769(5.85) | 267(2.94) | 408(4.27) | 269(5.36) | 387(6.36) | 855(7.83) | 583(8.77) | Â | |
Tyg_06 (mean (SD)) |  | 8.65(0.68) | 8.31(0.57) | 8.45(0.57) | 8.47(0.61) | 8.81(0.71) | 8.91(0.68) | 8.97(0.69) | < 0.001 |
Tyg_08 (mean (SD)) |  | 8.67(0.68) | 8.34(0.53) | 8.43(0.52) | 8.36(0.56) | 8.88(0.70) | 8.99(0.69) | 8.98(0.69) | < 0.001 |
Tyg_10 (mean (SD)) |  | 8.70(0.67) | 8.39(0.54) | 8.50(0.55) | 8.51(0.57) | 8.83(0.69) | 8.96(0.69) | 9.00(0.70) | < 0.001 |
CumTyG (mean (SD)) |  | 8.79(1.19) | 7.90(0.49) | 7.93(0.51) | 7.91(0.51) | 9.53(0.96) | 9.68 (1.03) | 9.74(1.10) | < 0.001 |
CRP_06(median [IQR]) |  | 0.72[0.28,2.00] | 0.30[0.11,0.60] | 0.79[0.30,1.80] | 3.40[0.93,7.90] | 0.31[0.17,0.60] | 0.90[0.41,1.70] | 3.24[1.27,7.23] | < 0.001 |
CRP_08 (median [IQR]) |  | 1.55[0.80,3.20] | 0.68[0.40,0.98] | 1.99[1.27,2.90] | 5.10[3.43,8.80] | 0.64[0.40,0.90] | 1.70[1.18,2.50] | 4.90[3.20,7.60] | < 0.001 |
CRP_10 (median [IQR]) |  | 1.10[0.50,2.53] | 0.50[0.20,0.90] | 1.30[0.69,2.63] | 3.30[1.20,7.02] | 0.57[0.27,0.92] | 1.30[0.77,2.30] | 3.10[1.40,5.90] | < 0.001 |
CumhsCRP (median [IQR]) |  | 1.53[0.83,2.97] | 0.59[0.40,0.78] | 1.64[1.28,2.12] | 5.02[3.77,7.87] | 0.67[0.49,0.84] | 1.71[1.32,2.22] | 5.03[3.80,7.33] | < 0.001 |